瑞芬太尼联合丙泊酚在宫腔镜手术中的应用效果及安全性分析

Efficacy and safety of remifentanil combined with propofol on hysteroscopic surgery

目的探讨瑞芬太尼联合丙泊酚在宫腔镜手术中的应用效果及安全性分析。方法选取2012年1月—2014年9月南京市雨花医院行宫腔镜手术的患者64例,按照随机数字表法分为A组与B组,各32例。A组患者采用瑞芬太尼联合丙泊酚麻醉,B组患者采用地佐辛联合丙泊酚麻醉,比较两组患者麻醉诱导1min、术中扩宫颈时平均动脉压(MAP)、心率(HR)水平、麻醉效果及并发症发生情况。结果麻醉诱导1min时,两组患者MAP和HR水平比较,差异无统计学意义(P>0.05);扩宫颈时,A组MAP和HR水平低于B组(P<0.05)。两组患者麻醉优良率比较,差异无统计学意义(P>0.05)。A组患者呼吸抑制、宫缩痛发生率低于B组,差异有统计学意义(P<0.05)。结论宫腔镜手术应用瑞芬太尼联合丙泊酚进行静脉麻醉的效果良好,术后并发症少。

Objective To investigate the efficacy and safety of remifentanil combined with propofol on hysteroscopic surgery. Methods A total of 64 cases of patients undergoing hysteroscopic surgery were selected from January 2012 to September 2014 in Nanjing Yuhua Hospital,which were randomly divided into A group and B group,32 cases in each group. A group was given remifentanil and propofol anesthesia,B group was given dezocine and propofol anesthesia. The MAP,HR were compared between the two groups at the time of 1min induced anesthesia and arterial dilation,and anesthesia effect and the incidence of complications were compared between the two groups. Results No statistically significant differences of MAP and HR between the two groups at the time of 1 min induced anesthesia( P > 0. 05); when arterial dilation,MAP and HR levels of A group were lower B group( P < 0. 05). No statistically significant difference of anesthesia excellent rate was found between the two groups( P > 0. 05). The incidence of respiratory depression and uterus systole pains were lower than B group( P < 0. 05).Conclusion The effect of remifentanil combined with propofol on hysteroscopic surgery is good,and with less postoperative complications.