早产儿颅内出血的相关因素分析及临床结局

Related factors and clinical outcomes of intracranial hemorrhage in preterm infants

目的分析早产儿颅内出血的相关因素及临床结局。方法选择医院收治的颅内出血的早产儿46例作为出血组,另选择身体健康的早产儿46例作为健康组,分析颅内出血的相关因素。结果出血组阴道分娩、胎儿窘迫、低体质量、机械通气、酸中毒、胎龄<32周、胎膜早破、妊娠期高血压疾病占比均高于健康组,差异均有统计学意义(P<0.05)。Logistic回归分析显示,低体质量、机械通气、妊娠期高血压疾病、胎儿窘迫及胎膜早破是导致早产儿发生颅内出血的危险因素。结论引发早产儿颅内出血的因素有很多,为保证母婴的健康与安全,应加强健康宣教,并根据颅内出血发生原因采取针对性的措施进行防治,以最大限度降低早产儿颅内出血发生率。

Objective To analyze the related factors and clinical outcomes of intracranial hemorrhage in premature infants.Methods 46 preterm infants with intracranial hemorrhage admitted to the hospital were selected as the bleeding group,and 46 healthy preterm infants were selected as the healthy group,the related factors of intracranial hemorrhage were analyzed.Results Vaginal delivery,fetal distress,low body mass,mechanical ventilation,acidosis,gestational age<32 weeks,premature rupture of membranes,and proportion of hypertensive disorder complicating pregnancy in the bleeding group were higher than those in the healthy group,the differences were statistically significant(P<0.05).Logistic regression analysis showed that low body mass,mechanical ventilation,hypertensive disorder complicating pregnancy,fetal distress and premature rupture of membranes were risk factors for intracranial hemorrhage in premature infants.Conclusion There are many factors causing intracranial hemorrhage in premature infants.In order to ensure the health and safety of mother and baby,the hospital should take the initiative to strengthen health education and take preventive measures according to the causes of intracranial hemorrhage,so as to minimize the incidence of intracranial hemorrhage in preterm infants.