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胰岛素泵与皮下注射胰岛素治疗糖尿病临床效果比较 被引量:7

Comparison of clinical effects between insulin pump and subcutaneous injection of insulin in the treatment of diabetes mellitus
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摘要 目的比较胰岛素泵与皮下注射胰岛素治疗糖尿病的效果。方法选取医院2015年7月-2018年5月收治的糖尿病患者78例,随机分为观察组与对照组各39例,观察组采用胰岛素泵治疗,对照组采用皮下注射胰岛素治疗,比较2组患者血糖控制情况及并发症发生情况。结果观察组平均胰岛素用量、空腹血糖均低于对照组,血糖达标时间短于对照组,差异均有统计学意义(P<0.05)。观察组酮症酸中毒与低血糖发生率低于对照组,差异均有统计学意义(P<0.05)。结论胰岛素泵治疗糖尿病能够加强血糖控制,降低并发症发生率,具有临床推广价值。 Objective To compare the effect of subcutaneous insulin injection and insulin pump in the clinical treatment of diabetes.Methods 78 patients with diabetes admitted to the hospital from July 2015 to May 2018 were selected,and they were randomly divided into observation group(39 cases)and control group(39 cases),the observation group was treated with an insulin pump,the control group was treated with subcutaneous injection of insulin,the blood glucose control and complications of the two groups were compared.Results The average insulin dosage and fasting blood glucose in the observation group were lower than the control group,and the blood glucose compliance time was shorter than the control group,and the differences were statistically significant(P<0.05).The incidence of ketoacidosis and hypoglycemia in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).Conclusion Insulin pump can strengthen blood glucose control and reduce the incidence of complications in the clinical treatment of diabetes.
作者 向传平 谭海波 邹宏林 周伟 周翠萍 XIANG Chuanping;TAN Haibo;ZOU Honglin(Endocrinology,The First People's Hospital of Yidu,Hubei Province,Yidu 443300,China)
出处 《临床合理用药杂志》 2019年第16期10-11,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 糖尿病 胰岛素 皮下注射 胰岛素泵 治疗效果 Diabetes Insulin Subcutaneous injection Insulin pump Therapeutic effect
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  • 1庞建华,王战建,吕璇.胰岛素泵治疗2型糖尿病28例疗效观察[J].中国全科医学,2004,7(12):916-916. 被引量:36
  • 2周泽华,况小璐,肖蓉.短期应用胰岛素泵输注人胰岛素类似物对初诊2型糖尿病患者胰岛β细胞功能影响的观察[J].重庆医学,2006,35(10):890-891. 被引量:7
  • 3董玉英,马晓玲,李双弟,夏瑾,申玉红,徐先明,江明礼.糖尿病合并妊娠83例母婴并发症分析[J].上海医学,2006,29(7):458-461. 被引量:15
  • 4李光伟,宁光,周智广.2型糖尿病早期胰岛素强化治疗改善胰岛β细胞功能——是现实还是梦想?[J].中华内分泌代谢杂志,2006,22(4):309-312. 被引量:223
  • 5Inzucchi S E,Bergenstal R M,Buse J B,et al.Man-agement of hyperglycaemia in type 2diabetes:apatient-centered approach.Position statement of the AmericanDiabetes Association(ADA)and the European Associa-tion for the Study of Diabetes(EASD)[J].Diabetolo-gia,2012,55(6):1577-1596.
  • 6DCCT Research Group.Diabetes Control and Complica-tions Trial(DCCT):the effect of intensive treatment ofdiabetes on the development and progression of long-term complications in insulin dependent diabetes melli-tus[J].N Engl J Med,1993,329(14):977-86.
  • 7Turnbull F M,Abraira C,Anderson R J,et al.Inten-sive glucose control and macrovascular outcomes in type2diabetes[J].Diabetologia,2009,52(11):2288-2298.
  • 8Rensing K L,von der Thüsen J H,Weijers E M,et al.Endothelial insulin receptor expression in human athero-sclerotic plaques:linking micro-and macrovascular dis-ease in diabetes?[J].Atherosclerosis,2012,222(1):208-215.
  • 9Obrosova IG.Diabetes and the peripheral nerve[J].Biochimica et Biophysica Acta(BBA)–Molecular Ba-sis of Disease,2009,1792(10):1-39.
  • 10Zhang Z,Liew CW,Handy DE,et al.High glucose in-hibits glucose-6-phosphate dehydrogenase,leading toincreased oxidative stress andβ-cell apoptosis[J].TheFASEB Journal,2010,24(5):1497-1505.

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