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血清肿瘤标志物联合检验诊断结直肠癌的价值 被引量:3

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摘要 目的分析血清肿瘤标志物联合检验诊断结直肠癌的价值。方法选择2016年1月-2017年12月医院接收的结直肠癌患者69例为观察组,另选择同期健康体检者69例为对照组,2组均行血清肿瘤标志物检验,比较2组血清肿瘤标志物水平,比较结直肠癌患者血清肿瘤标志物单项与联合检验的阳性诊断率及各期患者血清肿瘤标志物表达情况。结果观察组结直肠癌患者血清癌胚抗原(CEA)、糖类抗原(CA199、CA125、CA72-4)表达水平均高于对照组,差异有统计学意义(P<0.05)。联合检验的阳性诊断率均高于单项检验(P<0.05)。随着结直肠癌患者病情进展,CEA、CA199、CA125表达水平呈不断上升趋势,差异均有统计学意义(P<0.05)。结论血清肿瘤标志物联合检验效果优于单项检验,在结直肠癌患者诊断中具有较高的应用价值。
出处 《临床合理用药杂志》 2019年第25期117-118,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1Liao, Quan,Zhao, Yu-Pei,Yang, Ying-Chi,Li, Li-Jun,Long, Xiao,Han, Shao-Mei.Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head[J].Hepatobiliary & Pancreatic Diseases International,2007,6(6):641-645. 被引量:27
  • 2蒋志军,周维新,林伟,黄乾雄.多肿瘤标志物蛋白质芯片诊断系统在肠道肿瘤检测中的应用[J].现代检验医学杂志,2005,20(1):17-19. 被引量:6
  • 3牟江洪,李增鹏,王东,马瑜,肖华亮,张沁宏.大肠癌多种肿瘤标志物蛋白芯片联合检测及其在诊断中的意义[J].消化外科,2005,4(4):268-270. 被引量:21
  • 4Deng B G,Yao J H,Liu Q Y,et al.Comparative Serum Proteomic Analysis of Serum Diagnosis Proteins of Colorectal Cancer Based on Magnetic Bead Separation and MALDI-TOF Mass Spectrometry[J].Asian Pac J Cancer Prev,2013,14(10):6069.
  • 5Michl M,Koch J,Laubender R P,et al.Tumor markers CEA and CA 19-9 correlate with radiological imaging in metastatic colorectal cancer patients receiving first-line chemotherapy[J].Tumor Biol,2014,35(10):10121.
  • 6Duffy M J,van Dalen A,Haglund C,et al.Clinical utility of biochemical markers in colorectal cancer:European Group on Tumour Markers(EGTM)guidelines[J].Eur J Cancer,2003,39(6):718.
  • 7Tseng J Y,Yang C Y,Liang S C,et al.Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases[J].Clin Cancer Res,2014,20(11):2885.
  • 8Berkovich L,Shpitz B,Ghinea R,et al.Evaluation of peritoneal CEA levels following colorectal cancer surgery[J].J Surg Oncol,2014,110(4):458.
  • 9Zhang S,Chen Y,Zhu Z,et al.Differential expression of carbohydrate antigen 19 9 in human colorectal cancer:A comparison with colon and rectal cancers[J].Mol Clin Oncol,2013,1(6):1072.
  • 10Prager G W,Braemswig K H,Martel A,et al.Baseline carcinoembryonic antigen(CEA)serum levels predict bevacizumab-based treatment response in metastatic colorectal cancer.[J].Cancer Sci,2014,105(8):996.

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