下呼吸道感染细菌对常用抗生素耐药情况分析

Antibiotic Resistance of Bacteria Causing Lower Respiratory Tract Infections

目的 :探讨下呼吸道细菌感染病原菌对常用抗生素的耐药情况及预防措施。方法 :收集 10 7例下呼吸道感染细菌检出阳性的合格标本 ,其中血标本 3例 ,痰标本 10 4例 ,测定病原菌对常用抗生素的耐药情况。结果 :10 7例标本分离出病原菌 40种 ,12 7株 ,革兰阳性菌 5 4株 ( 4 2 .5 % ) ,革兰阴性菌 64株 ( 5 0 .4% ) ,真菌 9株 ( 7.1% )。药物敏感试验显示大多数病原菌对多种抗生素产生耐药。结论 :要减少或延缓下呼吸道感染耐药菌的产生 ,抗生素治疗原则需要做出相应的调整。

Objective:To study the antibiotic resistance of bacteria causing infections of the lower respiratory tract. Methods:Sputum or blood samples from 107 patients with bacterial infections of the lower respiratory tract positive for the causative bacteria were collected. Resistance of the bracteria to antibiotics in common use was assayed. Results:In the causative microbes recovered from the 107 positive sputum or blood samples, 127 bacteria, 40 types, Gram positive bacteria accounted for 42.5%, gram negative bacteria 50.4%, and fungi 7.1%. As shown by drug sensitivity tests, most of the pathogens were resistant to many kinds of antibiotics. Conclusion:A readjustment in the principles of treatment with antibiotics should be made in order to decrease or put off the occurrence of resistance of bacteria causing lower respiratory infections to antibiotics.