初期诊断的消化道恶性肿瘤病人的症状特征和生命质量研究

An Investigation on Symptom Characteristics and Life Quality of Patients With Newly Diagnosed Gastrointestinal Malignant Tumor

目的 :调查初期诊断的消化道恶性肿瘤病人半年中的症状特征和生命质量变化。方法 :采用MSAS症状评估量表和CARES -SF对 14 6例初期诊断的消化道恶性肿瘤病人的症状特征和生命质量进行为期半年的追踪调查。采用“WHO -QOL跨文化生命质量研究问卷翻译法”对调查表进行系统翻译和评价。结果 :初期诊断的消化道恶性肿瘤病人的生命质量为中等 ,半年内最突出的症状是乏力 ,其发生率、出现频度、严重程度和对病人造成的困扰程度也较高 ,失眠是使病人感到最困扰的问题 ,其他值得注意的症状有疼痛、体重减轻、口干、食欲下降。症状的发生率较稳定 ,但症状出现的频繁程度、严重程度和造成的困扰程度有较大的个体差异 ,没有明显的变化规律 ,症状维度与健康相关生命质量得分均呈中度相关。结论 :初期诊断的消化道恶性肿瘤病人在症状控制方面有特殊的需求 ,应持续评估病人的症状体验和生命质量 。

Objective: to investigate both symptom characteristics and quality of life changes of patients who were newly diagnosed with gastrointestinal tract malignant tumor over a six months period. Methods: a total of 146 newly diagnosed patients were selected, both symptom characteristics and quality of life of them were investigated and followed up for six months via filling out MSAS and CARES-SF. The questionnaire was translated and evaluated by adopting “WHO-QOL trans-culture life quality questionnaire translation”. Results: patients of newly diagnosed with gastrointestinal tract malignant tumor had a moderate level of life quality at their initial stage. Within the first six months, the most prevalent symptom of them was fatigue, which with a higher prevalence, frequency, severity and disturbance. Insomnia was the most disturbed symptom of these patients. Other symptoms of relative high in prevalence were including pain, weight loss, dry mouth and lack of appetite. Patients had a relatively stable symptom occurrence over six months' follow-up. But there were greater individual variations in terms of their symptom frequency, severity, and disturbance. Symptom variables of these patients were moderately correlated with their health related quality of life (HRQOL) scores. Conclusion: patients of newly diagnosed with gastrointestinal tract malignant tumors have some special demands for their symptom control. One should evaluate the symptom experiences and life quality of patients continuously and make out intervention program to enhance life quality of tumor patients.