摘要
目的研究巴布剂基质的最佳配方。方法采用正交设计法以黏着力为指标,对巴布剂基质配比进行实验研究。结果优化的基质配方为胶液∶甘油∶聚乙烯醇=5∶4∶0.2。结论优化处方具有良好的涂展性、保湿性,且黏着力适中。
Objective To choose the optimum matrix formulation of cataplasm. Method Orth ogonal design was used with the adhesion force as the index in the experiment. Results The optimum proportion of polymer solution, glycerin, polyvinyl alcohol is 5:4:0.2. Conclusion The optimum formulation is of moderate viscosity with good spreadable and humectant properties.
出处
《中国药剂学杂志(网络版)》
2004年第3期35-37,共3页
Chinese Journal of Pharmaceutics:Online Edition
关键词
药剂学
巴布剂
基质配方
正交设计法
黏着力
pharmaceutics
cataplasm
matrix formulation
orthogonal design
adhesion force