摘要
目的 :合成 1 氨基茚。方法 :以苯丙酰氯为初始原料 ,经 3步反应合成 1 氨基茚。由TLC确定每步反应终点。结果 :目标化合物结构经MS确证 ,纯度经GS MS测定达 97.8%。结论 :该法合成了 1 氨基茚 ,收率达 39.2 %。
Objective:To synthesize 1 aminoindan.Methods:1 Aminoindan was synthesized from 3 phenylpropionyl chloride by three unite reaction.The end up of reaction was determined by TLC.Results:The structure of the interesting compound was confirmed by MS,purity measured by GS MS was 97.8%?Conclusion:1 Aminoindan is syhthesized in this route with the yield of 39.2%.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2003年第6期457-458,共2页
Chinese Journal of New Drugs