期刊文献+

1-氨基茚的合成 被引量:4

Synthesis of 1-aminoindan
下载PDF
导出
摘要 目的 :合成 1 氨基茚。方法 :以苯丙酰氯为初始原料 ,经 3步反应合成 1 氨基茚。由TLC确定每步反应终点。结果 :目标化合物结构经MS确证 ,纯度经GS MS测定达 97.8%。结论 :该法合成了 1 氨基茚 ,收率达 39.2 %。 Objective:To synthesize 1 aminoindan.Methods:1 Aminoindan was synthesized from 3 phenylpropionyl chloride by three unite reaction.The end up of reaction was determined by TLC.Results:The structure of the interesting compound was confirmed by MS,purity measured by GS MS was 97.8%?Conclusion:1 Aminoindan is syhthesized in this route with the yield of 39.2%.
出处 《中国新药杂志》 CAS CSCD 北大核心 2003年第6期457-458,共2页 Chinese Journal of New Drugs
关键词 1-茚酮 1-氨基茚 合成 indanone 1 aminoindan synthesis
  • 相关文献

参考文献5

  • 1Benjamin S,Sasson C,Tzipora S, et al. Preparation and pharmacological use of N-acyl-1H-aminoindenes [ P]. WO: 0038673,2000 - 07 - 06.
  • 2Buckingham J. Dictionary of organic compounds 5th ed [ M ]. New York:Chapman and Hall, 1982. 3303.
  • 3Kotera K, Miyazaki S, Takahashi H, et al. Aziridine formation by lithium aluminum hydride reduction of oxirnes[J ]. Tetrohedron,1968,24(9) :3681 - 3696.
  • 4Feuerb H, Vincent B F, Bartlett B S. The reduction of oximes with diborane: a new synthesis of N-monosubstituted hydroxylamines[ J ]. J Org Chem, 1965,30 (9) : 2877 - 2880.
  • 5Shinzo K, Yasuyuki T, Eiichi S, et al. Reduction of some functional groups with titanium ( Ⅳ ) chloride/sodium borohydride [ J ].Communication, 1980, (9) :695 - 697.

同被引文献14

引证文献4

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部