多途径介入治疗37例急性坏死性胰腺炎的临床分析

Clinic analysis of multiple interventional ways treating 37 cases with acute necrotic pancreatitis

目的 :探讨经多途径介入治疗急性坏死性胰腺炎的效果。方法 :回顾性总结 6 7例用不同方法治疗的急性坏死性胰腺炎患者资料 ,其中介入组 (采用胰腺动脉插管灌注奥曲肽、抗生素、地塞米松、普鲁卡因四联药物 ) 37例 ,对照组 (四联药物静脉给药 ) 30例。结果 :介入组腹痛缓解、胰淀粉酶恢复正常及住院时间均短于对照组 (P<0 .0 5或 P<0 .0 1) ,两组严重并发症的发生率 (分别为 19.4 4 %和 4 1.93% )及病死率 (分别 2 .70 %和16 .6 7% )均有显著性差异 (P均 <0 .0 5 )。结论 :经多途径介入治疗急性坏死性胰腺炎较传统方法有效。

Objective: To investigate the effects of multiple interventional ways to treat acute necrotic pancreatitis(ANP). Methods: To study retrospectively different treatments for ANP, 37 patients were injected through pancreatic artery with octreotide, antibiotin dexamethasone, procaine, while 30 controls with traditional way. Results: For patients subjected with intervention, abdomen pain was released, amylopsin was normal, treating time was shorter than that of controls ( P <0 05 or P <0 01); the incidence of complications of intervention and control were 19 44 % and 41 93% respectively, and the mortality were 2 70% and 16 67%(all P <0 05). Conclusions: Interventional treatment for ANP is more effective than the traditional treatment.