心理应激对不同人格特质运动员TCD_4^+、TCD_8^+及IgG、IgA、IgM的影响

The effects of psychological stress on T-lymphocyte subsets and immunity globulin in athletes of different traits

目的探讨心理应激对不同人格特质运动员免疫功能的影响。方法用艾森克人格问卷(EPQ)测定29名运动员的人格特质。用比浊法测定IgG,IgA,IgM的含量;用免疫组化法测定T淋巴细胞亚群的数量。结果①心理应激能引起不同人格特质青少年射击运动员的免疫球蛋白含量和TCD4+,TCD8+及CD4+/CD8+比值发生变化。②安静状态下,人格特质对免疫应答的变化没有必然的联系;心理应激后,人格特质EPQL、EPQE显著性影响IgG的变化,人格特质EPQN显著性影响TCD4+的变化;而人格特质与IgA,IgM及TCD8+,TCD4+/TCD8+比值变化相关性不高。结论短时间心理应激刺激对不同人格特质青少年射击运动员的体液免疫与细胞免疫具有抑制作用,其生理机制与神经系统积极参与免疫调节有关。

Aim To explore the effects of psychological stress on immune function i n different traits of teenager shooters.Methods Eysenck personality questionnair e(EPQ) was conducted to estimate the traits of 29 athletes,14 males and 15 femal es with an average age of (15.9±1.8) years. The concentration of immune globuli n G,A and M and the number of T-lymphocyte subgroups were assayed by using turb idimetry and immunohistochemistry method respectively.Results (1) Psychological stress induced the variety of immunoglobulin concentration, and brought on perce ntage varieties of TCD4+,TCD8+,TCD4+/TCD8+.(2) In the calmness state, the tr aits had no certain relation to immune response. Being on psychological stress, the IgG concentration changed significantly related to EPQL and EPQE,and the var iety of TCD4+was significantly related with EPQN,but the traits showed no signi ficant correlation with the variety of the concentration of immune globulin A,M and the varieties of TCD4+,TCD8+,TCD4+/TCD8+.Conclusion The short-time psyc hological stress restrains the humoral immunity and cellular immunity in the tee nage gunshot athletes. The physiological mechanism of psychological stress is re lated with nervous system actively participating in the immunoloregulation.