论中药中各种化学元素有利于生命过程的必要条件——关于中药传统理论的当代化学物理及群子(量子)统计力学理论的诠释(Ⅰ)

Necessary Requirements Conducive to Life Process of Various Chemical Elements in Chinese Herbal Medicines ——Annotation of Traditional Theories of Chinese Herbal Medicines by Theories of Modern Chemistry, Physics and sub-cluster (quantum) statist

长期以来,中药的功效用深奥的中国古代哲学语言来描述,很少与现代物理化学理论有关联,致使中药学传统理论得不到应有的发展。作者深感有必要把中医中药学理论国际化,使东西方医学界都能够理解和接受,促进其发展。作者从现代化学物理论中的元素的氧化电位(V),含水络合离子的亲电性强度(ζ)及各种离子在水中的溶度积(pKps),各种离子对其它离子基因的络合能力(1gβ_1)的研究角度,提出了界定生命动力元素群和有毒元素群的定量方法,当运用量子统计力学的群子统计理论观察中药的阴阳性与药味之间关系,可发现中药中不同有机成份的形成与中药中生命动力元素群分布有密切的关系;当定量观察抗癌、抗心血管病、抗糖尿病等的中药的生命动力元素的分布与统计参数,定量地界定出这些药的功效与参数之间的定量关系,便可以将中药理论提升到当代化学物理及统计力学理论范畴来研究。由此可为中医药学现代化研究探索崭新的理论和方法论,并为进一步搞好抗癌、抗心血管病、抗糖尿病、抗艾滋病等中药的配方开辟了指导性思路。 本文是系列论文《关于中药传统理论的当代化学物理及群子(量子)统计力学理论的诠释》的首篇。

For a long time, the effectiveness of Chinese herbal medicines has been described by abstrusely ancient philosophical language. But it has hardly been associated with modern Chemical and physical theories so that due development has not been made in the traditional theories of Chinese pharmacology. The authors of this article deeply think that it is necessary to disseminate the theories of the science of traditional Chinese medicine to the whole world and Iet East and West medical circles mutually understand and exchange and accept each other so as to promote the development of both Eastern and Western medicines. Therefore, starting from the studies on the oxidation potential of elements, the electrophonic intensity of aqua complex ions, the solubility product of different ions in water and the complex ability of different ions for radical groups of other ions, they put fonvard the quantitative method for the definition of the group of life power elements and that of toxic elements: As the theory of sub-cluster statistics in quantum statistical mechanics is used for the observation of the relationship between the yin-yang nature and the medicines, it can be discovered that there exists a close relationship between the formation of different organic components and the distribution of the groups of life power elements in Chinese herbal medicines, and as the distribution and statistical parameters of life power elements of such Chinese herbal medicines as anti-cancers, anti-cardiovascular diseases and anti-diabetes are observed quantitatively and the quantitative relationship between the effectiveness and the parameters of the said medicines are defined quantitatively, the theories of Chinese herbal medicines can be up-graded to the theoretical domains of modern chemistry so as to explore completely new theories and methodologies of the modernization of Chinese pharmacology and to further open up guiding thoughts in making prescriptions of Chinese herbal medicines for anti-cancers, anti-cardiovascular diseases, anti-diabetes and Aids. This is the first one of the serial articles 'Annotation of Traditional theories of Chinese Herbal Medicines by Theories of Modern Chemistry, Physics and Sub-cluster (quantum) Statistical Mechanics' (7 articles in total, which will be published in this Journal continually) . It indicates that, if all the chemical elements as the nucleus of bioactivity in Chinese medicines have to become elements conducive to life process, at least eight requirements should be satisfied. For example, they are impossible to be precipitated together with OH and a large number of Cal in human body, impossible to be over-complex with all kinds of organic acids, and acyl keto group, impossible to be excessively affined with the monomers of amino acid in vivo, and impossible to be over-complex with the large quantity of amidogen groups existing in bio-protein molecules of human body. In addition, the ions of the elements in Chinese medicines, which are helpful to human life, cannot have actions to SH group in vivo. In this article all the elements are divided into the groups of useful and toxic ones in accordance with the complex ability of metai ions and their various groups and thus primary scientific basis is provided for the analysis of the cause of diseases from the angle of elements.