奥美拉唑与泮托拉唑治疗溃疡性上消化道出血的比较

Comparison omeprazole with pantoprazole effects on treating upper gastrointestinal peptic ulcer hemorrhage

目的 比较质子泵抑制剂奥美拉唑 (Ome)和泮托拉唑 (Panto)静脉滴注治疗消化性溃疡致上消化道出血的疗效及不良反应。方法 15 6例消化性溃疡致上消化道出血随机分为Ome组 74例和Panto组 82例分别使用Ome和Panto静脉滴注治疗。结果 两组中除分别有 2例和 3例需要加用其它药物或手术治疗外 ,均治愈。不良反应均较轻。结论 Ome和Panto均是治疗消化性溃疡致上消化道出血的首选药物 。

AIM To observe the effects and side effects on the patients with the upper gastrointestinal peptic ulcer hemorrhage in omeprazole(Ome) group and pantoprazole (Panto) group. METHODS\ 156 cases were randomly divided into Ome group 74 cases treated by Ome and Panto group 82 cases treated by Panto. RESULTS\ In Ome group,2 cases needed other treating method. In Panto group, 3 cases needed it. The adverse drug reactions in 2 groups were mild. CONCLUSION\ Ome and Panto have good therapeutic effects on the upper gastrointestional peptic ulcer hemorrhage and side effects are mild.