中国城乡脑中风的流行病学研究:1986年患病率分析

STUDY ON EPIDEMIOLOGY OF STROKE IN URBAN AND RURAL AREAS OF CHINA: AN ANALYSIS OF PREVALENCE RATES IN 1986

采用回顾性现况调查的方法,在全国范围内(台湾省未查)抽样调查了中国1986年12月31日完全性脑中风的时点患病率,调查当日样本人口数为5 814 851人,发现脑中风病例14 275例,患病率为245.49/10万,其95％置信区间为241.57～249.61/10万,用1986年中国城乡人口构成调整后为247.66/10万,用中国1982年人口标化后为191.92/10万,用世界人口标化后为259.86/10万。 分析发现,我国脑中风的患病率从南向北越来越高,从东向西越来越低。对经、纬度和脑中风患病率之间的关系,分别配合了线性回归模型,结果为:经度,Y=12.3819x-1107.381,tb=4.649,df=5,P=0.0056;纬度,Y=12.6279x-146.6266,tb=11.7517,df=4,P=0.0003。中国脑中风的患病率在不同地形地区差别显著;城市明显高于农村,男性显著高于女性。患病率随年龄的增长而上升,它们之间的关系可用Logistic曲线模拟。

Point prevalence rate of complete stroke on December 31, 1986 in China was investigated using a retrospecive section study for 5 814 851 people of 29 provinces and cities (excluding Taiwan province), and 14275 stroke cases were found. Point prevalence rate was 245.49 per 100000 people with 95% CI (confidence interval) 241.57-249.61 per 100000 people. The rate standardized by the constituent ratio of population between city and rural area of China in 1986 was 247.66 per 100000 people. The rate age-standardized by the population of China in 1982 accounted for 191.92 per 100000 and the rate agestandardized by the world standard population was 259.86 per 100000 people.It has also been found that there was a tendency for the prevalence rates to increase gradually from south to north and to decrease progressively from east to west. The linear regression models have been fitted between the point prevalence rates and latitude or longitude respectively. The results were Y= 12.3819×-1107.38 (tb = 4.65 df = 5 P = 0.0056) for longitudes and Y = 12.6279×-146.6266 (tb = 11.7517 df = 4 P = 0.0003) for latitudes. There was a difference statistically among various topographic areas. The prevalence rate was much higher in urban areas than rural areas and much higher in men than in women. The prevalence rate increased with age and their relationships have been fitted well with the logistic curve.