肝硬变患者食管曲张静脉破裂出血预测的研究

PREDICTION OF BLEEDING OF THE ESOPHAGEAL VARIX IN PATIENTS WITH CIRRHOSIS OF LIVER

对肝硬变患者217例于硬化剂治疗前行10项出血指标预测,观察与出血的关系。结果:出血组门静脉(PV)血管直径1.6±0.29cm、PV血流量986.5±117.8ml/min,术中PV游离压3.76±0.28kPa,食管曲张静脉压力3.56±0.25kPa。非出血组各值分别为1.40±0.16cm、831.7±53.6ml/min、2.79±0.33kPa及2.75±0.31kPa。两组相比差异非常显著(P<0.01)。曲张静脉≥Ⅲ级、扭曲状、红色征与≤Ⅱ级、直线扩张及非红色征出血发生率有非常显著差异(P<0.01～0.001)。

This article reports on 217 patients with cirrhosis before sclerotherapy. It was observed that there was relationship between the 10 indexes and bleeding, i.e. the diameter of portal vein in bleeding group 1.60±0.29 cm, portal venous flow 986.5±117.8 ml/min, free portal pressure 3.76±0.28 kPa, the esophageal variceal pressure 3.56±0.25 kPa. In the patients with no bleeding, the value were 1.40±0.16 cm, 831.7±53.6 ml/min, 2.79±0.33 kPa, and 2.75±0.31 kPa, respectively. Differences between two groups were significant (P<0.01). Varices≥III° with knotty appearance and 'red sign' are significatly different from varices≤II° without 'red sign' and straight appearance in incidence of bleeding.