摘要
本文分析了61例住院病人发生的66例次与产气肠杆菌相关的医院感染,其特点是:(1)感染部位多样,不仅见于肺部(30例次)、伤口(16例次)与尿路(11例次),还发生了败血症(9例次);(2)耐药菌株比例高,对氨苄青霉素、羧苄青霉素、链霉素与氯霉素的耐药率均在70%以上;(3)部分病人(26例)有混合感染,且90%系与其他革兰阴性杆菌的混合感染;(4)预后严重,本组有24例死亡,其中7例的死亡与此感染有密切关系;(5)由于基础疾病病情严重,73.8%的病人有抗菌药物预防史,平均用药3.86种,持续22.8d。作者认为,在控制医院感染中,应当重视产气肠杆菌感染的诊断与处理,并控制其传播,这是有现实意义的工作。
A total of 66 times of nosocomial infection with enterobacter aerogene were noted in 61 of our patients. The clinical features were: (1) varied sites of infection including lung (30/66), wound (16/66), urinary tract (11/66) and even septicaemia (9/66); (2) high prevalence of resistant-strains: accounting for over 70% of patients resistant to ampicillin, carbenicillin, streptomycine and chlo-romycetin;(3) mixed-infection with gram-negative bacilli in 26 patients; (4) poor prognosis in that nosocomial infection with enterobacter aerogenes was responsible for the death of 7 patients among 24 of the 66 who died; (5) preventive antibiotics necessary in 73.8% of patients because of serious condition. Our investigation suggests that some diagnostic and therapeutic measures should be taken to prevent anp control nosocomial infection with enterobacter aerogenes.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
1992年第6期434-436,共3页
Medical Journal of Chinese People's Liberation Army
关键词
产气肠杆菌
医院感染
Enterobacter aerogenes
Nosocomial infection