肌注大剂量强的松龙后大鼠胃肠道内分泌细胞分布的变化

CHANGE OF ENDOCRINE CELLS OF GASTROINTESTINAL TRACT IN POPULATION AFTER INJECTION OF PREDNISOLONUM

本文采用组织化学和免疫组织化学的方法,对10只6～7周S.D大鼠肌注大剂量强的松龙3周后,胃肠道内嗜银细胞和5-羟色胺细胞分布变化进行了统计和对比观察。结果表明:实验组内分泌细胞在胃肠各段的分布密度曲线与对照组明显不同,内分泌细胞分布的变化可能与全身或胃肠道免疫功能有关;胃窦和肠道内的嗜银细胞分布情况与5-羟色胺细胞相似,其分布基本上能反映出Ec细胞的分布。

This presemt study would abserve the change of argyrophil cells and immunoreactive serotonin (irSer) cells for 10 S.D rats with 6-7 weeks of age after intramuscular injection of prednisolonum for three weeks with histochemical and immunohistochemical techniques. The results revealed that the cures of population in each segment of GI were different between two groups. The change of endocrine cells in population might be relative to immunity of body or GI tract. The distribution of argyrophil cells in gastric antrum and intestine was consistant with that of irSer cells which indicated that it might give expression to the distribution of EC cells.