发疱式自体表皮移植术治疗白癜风的临床观察

CLINICAL OBSERVATION OF AUTOLOGOUS EPIDERMIC GRAFTING WITH SUCTION BLISTERS FOR THE TREATMENT OF VITILIGO

目的 :探讨发疱式表皮移植术治疗白癜风的疗效及副作用。方法 :对 83例稳定期白癜风患者采用发疱式自体表皮移植术 ,植入直径 8mm～ 10mm皮片 35 2片 ,对特殊部位白斑于术前采用冷冻或高频电方法祛除表皮。结果 :皮片存活率 96 .0 2 % ,总有效率 89.77%。 10 6片 (2 9.36 % )供皮区出现色素沉着 ,所有植皮区、供皮区均无瘢痕形成或同形反应发生。结论 :发疱式自体表皮移植术是安全、简便。

Objective:To investigate the effectiveness and complications of epidermic grafts in patients with vitiligo.Methods:Epidermal grafting with suction blisters was performed on 83 patients with stable vitiligo. 352 skin grafts, each sizes 8～10mm, were transplanted. Some vitiliginous lesions in peculiar areas were previously dermabraded with cryotherapy or electrocauterization.Results:Clinical response and side effects were evaluated. The revivability of grafts was 96.02%, the total success rate was 89.77%. Neither scar formation nor Koebnerization was noted in the sites of acceptors or donors. Hyperpigmentation appeared at 106 doners sites (29.36%) was the only adverse effect.Conclusions:Autologous epidermal grafting is a safe,simple and effective technique for vitiligo.