3Murray KJ, Moroldo MB, Dormelly P, et al. Age-specific effects of juvenile rheumatoid arthritis-associated HLA alleles. Arthritis Rheum, 1999,42:1843-1853.
4Grom AA,Hirsch R.T-cell and T-cell receptor abnormalities in the immunopathogenesis of juvenile rheumatoid arthritis. Curr Opin Rheumatol, 2000,12: 420-424.
5Huang JL, Kuo ML, Hung IJ, et al. Lowered IL-4-producing T cells and decreased IL-4 secretion in peripheral blood from subjects with juvenile rheumatoid arthritis. Chang Gung Med J,2001,4:77-83.
6Wedderburn LR, Patel A, Varsani H, et al. Divergence in the degree of clonal expansions in inflammatory T cell subpopulations mirrors HLA-associated risk alleles in genetically and clinically distinct subtypes of childhood arthritis. Int Immunol,2001,13: 1541-1550.
7Thompson SD, Luyrink LK, Graham TB, et al. Chemokin receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4 : IFN-gamma mRNA ratios. J Immunol, 2001,166:6899-6906.
8Dong X, Wang J, Kabir FN, et al. Autoantibodies to DEK oncoprorein in human inflammatory disease. Arthritis Rheum, 2000,43: 85-93.
9Hromadnikova I, Vavrineova P,Stechova K, et al. Anti-keratin antibodies in patients with juvenile idiopathic arthritis. Clin Exp Rheumatol, 2001,19: 470-473.
10Khalkhali-Ellis Z, Bulla GA, Schlesinger LS, et al. Clq-containing immune complexes purified from sera of juvenile rheumatoid arthritis patients mediate IL-8 production by human synoviocytes: role of C1q receptors. J Immunol, 1999,163:4612-4620.
3Fink C and the Task Force for Classification Criteria.Proposal for the development of classification criteria for idiopathic arthritis of childhood:Santiago,1994.J Rheumatol,1995,22:1566-1569.
4Petty R and the Task Force for Classification Criteria.Revision of the proposed classification criteria for juvenile idiopathic arthritis:Durban,1997.J Rheumatol,1998,25:1991-1994.
7de Kleer IM,Wedderburn LR,Taams LS,et al.CD4^+ CD25 bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis[J].J Immunol,2004,172(10):6435-6443.
8Wulffraat NM,de Kleer IM,Prakken B.Refractory juvenile idiopathic arthritis:Using autologous stem cell transplantation as a treatment strategy[J].Expert Rev Mol Med,2006,8(26):1-11.
9Ruprecht CR,Gattorno M,Ferlito F,et al.Coexpression of CD25 and CD27 identifies FoxP3^+ regulatory T cells in inflamed synovia[J].J Exp Med,2005,201(11):1793-1803.