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Study on the NO Concentration and NOS Activity in the Serum and Tissues of Ducklings with Selenium Poisoning

Study on the NO Concentration and NOS Activity in the Serum and Tissues of Ducklings with Selenium Poisoning
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摘要 One-day-old healthy ducklings(n=100)were divided into control group and experimental group randomly, and selenium poisoning of ducklings was artificially caused by feeding ration containing 8 mg kg-1 Se every day. The dynamic changes of No content and NOS activity in the serum and tissues were determined by means of the method of nitric acid reductase. Results showed that the NO content and NOS activity in serum and tissues in experimental group increased significantly(P<0. 05)and they were time-dependent. It was suggested that the high level of selenium in bodies could increase the NOS activity and NO content as it destroyed the metabolism of material and energy as well as structure and function of tissues and cells. These changes of NO content and NOS activity might be involved in the metabolism of selenium poisoning. One-day-old healthy ducklings(n=100)were divided into control group and experimental group randomly, and selenium poisoning of ducklings was artificially caused by feeding ration containing 8 mg kg-1 Se every day. The dynamic changes of No content and NOS activity in the serum and tissues were determined by means of the method of nitric acid reductase. Results showed that the NO content and NOS activity in serum and tissues in experimental group increased significantly(P<0. 05)and they were time-dependent. It was suggested that the high level of selenium in bodies could increase the NOS activity and NO content as it destroyed the metabolism of material and energy as well as structure and function of tissues and cells. These changes of NO content and NOS activity might be involved in the metabolism of selenium poisoning.
出处 《Agricultural Sciences in China》 CAS CSCD 2003年第6期682-686,共5页 中国农业科学(英文版)
关键词 DUCKLING SERUM Selenium poisoning Tissue Nitric oxide Nitric oxide synthase Duckling, Serum, Selenium poisoning, Tissue, Nitric oxide, Nitric oxide synthase
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