运动训练对大鼠锌铜代谢及血清ALP,LDH活性影响的研究

Effects of Exercise Training on Zinc, Copper Metabolism and Activities of Serum Alkaline Phosphatase, Lactate Dehydrogenase in Rats

通过对大鼠1次力竭性游泳和4周耐力性游泳训练后锌、铜代谢及血清碱性磷酸酶(ALP)、乳酸脱氢酶(LDH)活性变化的研究,结果发现:1)1次力竭性游泳运动导致大鼠锌、铜在体内重新分配,即通过血液运输,从骨骼肌向肝脏、心脏转移。2)4周耐力性游泳训练使大鼠机体增加对锌的储存,大鼠不表现锌缺乏,但大鼠体内铜储量下降,有导致缺乏可能。3)1次力竭性游泳运动后大鼠血清碱性磷酸酶、乳酸脱氢酶活性升高,但这些酶活性的升高与血清锌浓度上升没有明显相关关系。4)4周耐力性游泳训练使大鼠安静时血清乳酸脱氢酶活性升高,说明长期耐力运动有选择性导致某些血清酶活性升高的可能。

The changes of zin (ZN), copper (Cu) metabolism and activities of serum alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) were studied in rats after an exhaustive swimming and 4 weeks of endurance swimming training. The results showed: 1. An exhaustive swimming induced the redistribution of Zn and Cu in the body, that is the Zn and Cu transferred by blood transportation from the skeletal muscles to the liver and the heart. 2. The deposited Zn in the body of the rats increased after four weeks of endurance swimming training without the shortage of Zn. But the deposited Cu in the body of the rats decreased, which is possible to induce the shortage of Cu. 3. The activities of the serum alkaline phosphatase and lactate dehydrogenase of the rats increased after an exhaustive swimming, but there was no remarkable correlativity between the increase of those enzyme activities and the rise of the serum Zn concentration. 4. The serum lactate dehydrogenase activity increased at rest after four weeks of endurance swimming training, showing that the longterm endurance training is possible to induce the rise of some serum enzyme activities selectively.