六味木香胶囊西咪替丁治疗反流性食管炎

Therapeutic Efficacy of Liuwei Muxiang Capsule & Cimitidin in Treatment of Reflux Esophagitis

目的 观察六味木香胶囊与西咪替丁联用治疗反流性食管炎的临床疗效。方法 将 10 4例内镜诊断反流性食管炎患者随机分为两组 ,治疗组 56例 ,六味木香胶囊 5粒 ,每日 2次 ,西咪替丁 80 0mg ,每晚睡前 1次 ,口服 ;对照组 48例 ,单服同剂量西咪替丁 ,疗程均为 4周。结果 两组症状控制总有效率分别为 96 3 %和54 1% (P <0 0 1) ,内镜改善总有效率分别为 94%和 60 % (P <0 0 5)。结论 六味木香胶囊与西咪替丁联用是治疗反流性食管炎的理想方案。

Objective To observe the clinical effect of liuwei muxiang capsules and cimitidin on reflux esophagitis.Methods 104 patients with reflux esophagitis diagnosed by endoscopy were randomly divided into two groups. The treatment group(n=56) took liuwei muxiang capsules 3 ones bid and cimitidin 800mg qd,per os;the control group(n=48) received only cimitidin of the same dose,for 4 weeks.Results In the two groups the clinical improvement rates of 96.3 and 54.1 percent were attained respectively(P<0.01),and endoscopic amelioration rates were 94 and 60 percent respectively(P<0.05).Conclusions Liuwei muxiang capsules combined with cimitidin is the ideal therapeutic scheme for reflux esophagitis.