苦参素 甘利欣注射液治疗乙型肝炎

Clinical Observation of Chronic Hepatitis B Treated by Injection Oxymatrine and Diagly

目的 探讨苦参素注射液联合甘利欣注射液治疗乙型肝炎的疗效 ,寻找治疗乙型肝炎的有效方法。方法 将 10 3例乙型肝炎患者分为治疗组 55例和对照组 48例 ,治疗组应用苦参素注射液及甘利欣注射液 ,对照组应用甘利欣注射液 ,观察ALT及HBV -M的变化。结果 治疗结束时 ,治疗组HBeAg阴转率及ALT复常率均较对照组高 ,两组HBeAg阴转率分别为 3 2 7%、10 4% (P <0 0 1) ,ALT复常率分别为 94 5%、75 0 % (P <0 0 1)。

Objective To investigate the clinical effect of injection oxymantrine with injection diagly on viral hepatitis B.Methods 103 cases with hepatitis B were divided into treatment group and control group(55 cases for treatment group and 48 cases for control group).Injection oxyimatrine used with injection diagly in treatment group,and injection diagly was given in control group to observe ALT and HBV-M changes.Results At the end of treatment,the rate of normal ALT and the negative rate of HBeAg in treatment group were higher than that of control group.Between two groups,the negative rate of HBeAg is 32.7%、10.4%(P< 0.01 ),and the rate of normal ALT is 94.5%、75.0%(P<0.01).Conclusion Injection oxymatrine together with injection diagly is effective to treat hepatitis B with a good negative rate of HBeAg and the rate of normal ALT.