泌尿外科感染者致病菌的耐药分析

Analysis of Antibiotic Resistance of Clinic Pathogens in Urology

目的 了解泌尿外科感染者主要致病菌及致病菌的耐药现状。方法 收集本院泌尿外科 50 0株致病菌 ,采用K -B法进行药敏试验 ,用统计学原理进行统计 ,根据美国临床实验室标准委员会 (NCCLS)最新标准 ,判断细菌耐药性。结果 2 0 0 1～ 2 0 0 2年共检出泌尿外科 50 0株致病菌。主要致病菌是 :金黄色葡萄球菌 (金葡菌 ) ,凝固酶阴性葡萄球菌 (CNS) ,大肠埃希菌 ,变形杆菌属 ,肠球菌属等 ,其中真菌感染率比往年增高。金葡菌对甲氧西林的耐药率为 84 9% ,对阿奇霉素的耐药率为 91 4% ;CNS对阿奇霉素的耐药率为 92 9% ;两种致病菌对其他抗生素耐药性也在增加 ;肠杆菌科对氨苄西林的耐药率 >62 % ;致病菌对呋喃妥因、丁胺卡那、庆大霉素耐药率较低。结论 应重视泌尿外科感染者的致病菌及在治疗中致病菌耐药性监测工作 。

Objective To study the distribution of main clinic pathogens in urological Dept.Method 500 strains urological pathogens were collected and analysed at the antibiotic resistance with K-B method based on standards of NCCLS.Results 500 strains of main clinic pathogens isolated from urological samples:Staphylococcus Aureus,Coagulase Negative Staphylococus(CNS),Escherichia Coli,Proteus,Enterococcus,etc.ratio of the fungus infections is high this year.drug resistance of staphylococcus aureus to metocilin,azithromycin are 84.9%,91.4% respectviely,of CNS to azithromycin is 92.9%,drug resistance of two pathogens above mentioned to other drugs is increasing,Escherichia Coli Drug resistance is >62%,drug resistance of microorganism to nitrofurantioin,amikacin,gentomycin get low.Conclusion Ought to emphasize to drug resistance of clinic pathogens of infected cases in urology and to give the surveilliance of antibiotic resistance spectrum of bacterium.