肠易激综合征患者胃食管胆汁反流的临床意义

The study of gastroesophagel bile reflux in patients with irritable bowel syndrome

目的 探讨肠易激综合征患者胆汁反流的临床意义。方法 用便携式胆红素监测仪 (Bilitec 2 0 0 0 )对 2 4例确诊为肠易激综合征和 6例健康人进行 2 4h食管腔内胆红素监测。结果 肠易激综合征患者胆汁反流总时间 % (10 .11± 5 .82 )明显高于健康对照组 (4 .0 9± 2 .3 7) ;其中便秘型患者胆汁反流总时间 % (14 .0 9± 5 .3 9)显著高于腹泻型患者 (8.48± 5 .2 9)。结论 肠易激综合征患者中存在碱反流 。

Objective To evaluate the clinical role of bile reflux in irritable bowel syndrome(IBS).Methods 24 hours esophageal bilirubin levels were investigated in 24 patients with IBS and 6 healthy subjects with Bilitec 2000 apparatus.ResultsThe total fraction time of bile reflux was higher in patients with IBS than those in control (10.11±5.82 vs 4.09± 2.37); Patients with constipation predomin IBS has a higher total fraction time of bile reflux than those with diarrhea predominant IBS (14.09±5.29 vs 8.48±5.29).Conclusion Bile reflux were observed in patients with IBS,in particular,in patients with constipation predominant IBS.