急性心肌梗塞直接冠状动脉介入治疗的临床疗效观察

Clinical efficacy of emergency percutaneous coronary interventional technique

目的 :比较直接冠状动脉介入治疗 (PCI)与静脉溶栓治疗对急性心肌梗塞 (AMI)患者住院期间的临床效果。方法 :在 166例AMI患者中 ,86例患者直接PCI ,80例患者接受尿激酶溶栓治疗。结果 :溶栓梗塞组相关血管 (IRA)再通率 5 2例 ,再通率 62 % ;直接PCI组IRA成功开通 80例 ,成功率 10 0 % ,住院期间左室射血分数 (LVEF)溶栓组为 5 2 8± 10 1% ,直接PCI为 63 8± 9 6%差异有显著性 (P <0 .0 5 )。结论 :直接PCI与溶栓治疗AMI患者比较 ,前者能使IRA充分有效开通 ,可更好地改善患者的左心室功能。

Objective: To compare the clinical efficacy of emergency percutaneous coronary interventional technique(PCI) with thrombolytic therapy in the treatment of acute myocardial infarction (AMI).Methods: One hundred and sixty six consecutive patients with a first AMI underwent either intravenous UK (80 patients) or PCI (86 patients).Results: 82 patients were successfully treated by emergency PCI and the rates of successful treatment were 100%.The recanalizing rate of infarction related artery (IRA) in 80 patients with thrombolytic theraty was 62%.There were no significant differences image,risk factor,time from onset of symptom to hospital presentation and infarct location between the two groups but apparent differences were found in LVEF (63.8±9.6% vs 52.8±10.1%, P <0.05).Conclusion: Primary PCI is more effective than thrombolytic therapy in preserving cardiac function after AMI.Thrombolytic regimens compatible with subsequent interventions is an effective and safe therapy for AMI.