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Absence of sperm meiotic segregation error of chromosomes 1, 9,12,13,16,18, 21, X and Y in a case of 100% necrozoospermia 被引量:1

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摘要 <abstract>Varying degrees of necrozoospermia are common findings in cases of male sub-fertility; however, it is rare to find persistent and 100 % necrozoospermia. A case of persistent 100 % necrozoospermia is presented in this paper, where aneuploidy analysis was carried out on sperm. No known associations like thyrotoxicosis, genital infection, spinal injury and diabetes were found. Sperm fluorescent in situ hybridization (FISH) was carried out to evaluate sperm aneuploidy for chromosome 1, 9, 12, 13, 16, 18, 21, X and Y and did not show any excess of aneuploidy over controls. To the best of our knowledge, this is the first attempt on meiotic segregation analysis on 100 % necrozoospermic patient. <abstract>Varying degrees of necrozoospermia are common findings in cases of male sub-fertility; however, it is rare to find persistent and 100 % necrozoospermia. A case of persistent 100 % necrozoospermia is presented in this paper, where aneuploidy analysis was carried out on sperm. No known associations like thyrotoxicosis, genital infection, spinal injury and diabetes were found. Sperm fluorescent in situ hybridization (FISH) was carried out to evaluate sperm aneuploidy for chromosome 1, 9, 12, 13, 16, 18, 21, X and Y and did not show any excess of aneuploidy over controls. To the best of our knowledge, this is the first attempt on meiotic segregation analysis on 100 % necrozoospermic patient.
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2003年第2期163-166,共4页 亚洲男性学杂志(英文版)
关键词 OLIGOSPERMIA necrozoospermia fluorescent in situ hybridization <keyword>oligospermia necrozoospermia fluorescent in situ hybridization
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  • 1Tournaye H, Liu J, Nagy Z, Verheyen G, Van Steirteghem A,Devroey P. The use of testicular sperm for intracytoplasmic sperm injection in patients with necrozoospermia. Fertil Steril 1996; 66: 331-4.
  • 2Rives N, Saint Clair A, Mazurier S, Sibert L, Simeon N, Joly G,et al. Relationship between clinical phenotype, semen parameters and aneuploidy frequency in sperm nuclei of 50 infertile males. Hum Genet 1999; 105: 266-72.
  • 3World Health Organization. WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th edition, Cambridge:Cambridge University Press; 1999. p 60-1.
  • 4Halder A, Tutscheck B. Analysis of meiotic segregation in human nondecondensed interphase spermatozoa by triple color rapid direct fluorescent in sire hybridization. Indian J Med Res 1998; 107: 94-7.
  • 5Shen HM, Dai J, Chia SE, Lim A, Ong CN. Detection of apoptotic alterations in sperm in subfertile patients and their correlation with sperm quality. Hum Reprod 2002; 17: 1266-73.
  • 6Oosterhuis GJ, Mulder AB, Kalsbeek-Batenburg E, Lambalk CB, Schoemaker J, Vermes I. Measuring apoptosis in human spermatozoa: a biological assay for semen quality? Fertil Steril 2000; 74: 245-50.
  • 7Ricci G, Perticarari S, Fragonas E, Giolo E, Canova S, Pozzobon C, et al. Apoptosis in human sperm: its correlation with semen quality and the presence of leukocytes. Hum Reprod 2002; 17:2665-72.
  • 8Baccetti B, Collodel G, Piomboni P. Apoptosis in human ejaculated sperm cells(notulae seminologicae 9). J Submicrosc Cytol Pathol 1996; 28: 587-96.

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