期刊文献+

层粘连蛋白及其受体与宫颈上皮内瘤样病变和子宫颈癌

Laminin and laminin-receptor in cervical intraepithelial neoplasia and cervical carcinoma
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摘要 层粘连蛋白及其受体是一类广泛存在于基底膜带中的多功能大分子糖蛋白 ,近年来研究证明它们与肿瘤的浸润和转移密切相关 ,深入探讨层粘连蛋白及其受体粘着及与肿瘤的相互作用 ,将为进一步研究肿瘤的浸润及转移提供理论依据 ,本文就层粘连蛋白及其受体与宫颈上皮内瘤样病变和子宫颈癌的关系进行综述。 Laminin and laminin receptor are multifunctional giant molecule glycoproteins which exist in basal membrane at large. Recently, they have been proved to be associated with the carcinoma's invasion and metastasis.It will provide us a theoretical basis on the tumor's invasion and metastasis to study conglutination of laminin and laminin receptor and the mutual relation between they and tumor. This summary is to sum up the correlation of laminin and laminin receptor with cervical intraepithelial neoplasia and cervical carcinoma.
出处 《国外医学(妇幼保健分册)》 2003年第3期180-182,共3页 Foreign Medical Sciences (Section of Maternal and Child Health)
关键词 层粘连蛋白 层粘连蛋白受体 宫颈上皮内瘤样病变 子宫颈癌 laminin, laminin receptor, cervical intraepithelial neoplasia, cervical carcinoma
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参考文献18

  • 1Rajab TT, Pento JT. Influence of antiestrogens on invasiveness and laminin attachment of breast cancer cell[J]. Cancer Investigation, 1999,17(1) : 10 - 18.
  • 2Sorokin AV, Mikhailov AW, Kachko AV, et al. Human recombinant laminin-binding protain: isolation purification and crystallization [ J ]. Biochemistry (Mosc),2000,65(5) :546 - 553.
  • 3Virtanen I, Gullberg D, Rissanen J, etal. Laminin alphal-chain shows a restricted distribution in epithelial basement membranes of fetal and adult human tissues [J]. ExD Ceil Res,2000,257(2) :298 - 309.
  • 4Shi Y, Zhai H, Wang X, et al. Multidrug-resistanceassociated protein(McrI-Ag)is identical to human 37-kDa LN-R precursor[J]. Cell Mol Life Sci, 2002, 59(9): 1577 - 1593.
  • 5Iodugno I, Tagliabue E, Ardini E, et al. P53-depent downregulation of metastasis-associated laminin receptor[ J ]. Oneogene, 2002,21 (49): 7478 - 7487.
  • 6Fulop T, Larbi A. Putative role of 67kDa elastin-laminin receptor in tumor invasion[ J ]. Semin Cancer Biol, 2002,12(3) :219 - 229.
  • 7Hipfel R, Schittek B, Bodingbauer Y, et al. Specifically regulated genes in malignant melanoma tissues.identified by subtractive hybridization[J]. Br J Cancer,2000,82(6) : 1149 - 1157.
  • 8Gloe T, Pohl U. Laminin binding conveys mechanosensing in endothelial cells[J]. News Physiol Sei,2002, 17:166-169.
  • 9Davidson B, Goldberg L, Gotlieb WH, et al. Expresion of matris proteins in uterine cervical neoplasia using immunohistochemistry[ J ]. Ear J Obstet Gynecol Reprod Biol. 1998,76(1) :109 - 114.
  • 10Nair SA, Nair MB, Jayaprakash PG, et al. The basement membrane and tumor progression in the uterine cervix[J]. Gen Diagn Pathol, 1997, 142(5 - 6) :297 - 303.

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