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82例学龄前聋儿致聋危险因素的调查 被引量:6

Analysis of etiologic factors in childhood deafness
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摘要 目的 :探讨聋儿致聋的危险因素。方法 :采用问卷调查方式对 82例聋儿中可能存在的危险因素进行回顾性调查 ,并对较常见的一些因素在聋儿及配对的正常儿的分布进行多因素分析。结果 :82例学龄前聋儿中 ,含已知有危险因素者共 6 2例 (75 .6 % ) ,2 0例 (2 4 .4 % )未查及任何已知的危险因素。对危险因素的多因素分析表明氨基甙类药物的使用仍然是致聋的一个显著的危险因素。结论 :充分认识致聋的危险因素 ,注意克服与避免这些危险因素的危害 。 Objective:To study the etiologic factors in deafness children.Method:High risk factors were studied in 82 deafness children with speech and language impediment by a high risk scale to their parents. Stepwise logistic regression was used to identify variables associated with childhood deafness.Result:There were 108 risk factors founded in 62 cases. Aminoglycosides was proved to be a significant high risk for deafness.Conclusion:It is very important that ototoxic medications should be strictly controlled for pregnant woman and children in reducing the mobility of children's hearing loss.
出处 《临床耳鼻咽喉科杂志》 CAS CSCD 北大核心 2003年第7期419-420,共2页 Journal of Clinical Otorhinolaryngology
关键词 语言-言语发育障碍 耳聋 儿童 流行病学 危险因素 Speech and language impediment Deafness Children Epidemiology
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  • 1Salamy A, Eldredge L,Tooley W H. Neonatal status and hearing loss in high-risk infants. J Pediatr, 1989, 114 :847--847.
  • 2Borradori C,Fawer C L, Buclin T, et al. Risk factors of sensorineural hearing loss in preterm infants. Biol Neonate, 1997,71 : 1-- 10.
  • 3Prezant T R, Agpian J V, Bohlman M C, et al. Mitochondrial ribosomal RNA mutation assocated with both antibiotic-induced and non-syndromic deafness. Nat Genet, 1993,41289 -- 293.
  • 4Johnsonbaugh R E,Drexler H G,Light I J,et al. Familial occurrence of drug-induced hearing loss. Am J Dis Child, 1974,127 : 245 -- 245.

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