期刊文献+

围术期输血的合理应用 被引量:2

下载PDF
导出
摘要 1 转变围术期输血的传统观念 毋庸质疑,输血对于严重创伤大失血病人至关重要.但可能的副作用、花钱多、间断性的血源不足都要求我们要合理应用同种血源.对此加拿大的 Hebert等 [1] 的研究结果最具说服力,他们将 838例 ICU病人分为 2组(限制组:维持血红蛋白 70~ 90g/L,自由组:维持血红蛋白 100~ 120g/L),结果在限制组平均血红蛋白浓度 (85± 7)g/L,平均输血 2.6± 4.1U,未输 RBC者达到 33%;而自由组平均血红蛋白为 (107± 7)g/L,平均输血 5.6± 5.3U,未输 RBC者为 0%.限制组的 30天死亡率和自由组相似( 18.7% vs 23.3%) ,但住院死亡率、多器官功能异常评分以及肺水肿和心梗发生率,限制组明显低于自由组.可见,输血对于改善组织氧供、氧耗和病人预后的作用正面临挑战.
作者 王刚
出处 《中国航天医药杂志》 2003年第1期1-4,共4页 Medical Journal of CASE
  • 相关文献

参考文献14

  • 1[1]Hebert PC, Wells G, Blajchman MA, et al. The Transfusion Re-quirements in Critical Care Investigators for the Canadian Critical Care Trials Group: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med, 1999,340:409-417
  • 2[2]Goodnough LT, Brecher ME, Kanter MH, et al. Transfusion medicine: First of two parts-blood transfusion. N Engl J Med,1999, 340:438-447
  • 3[3]Moor AC, Dubbelman TM,VanSteveninck J, et al.Transfusion-transmitted diseases: Risks, prevention and perspectives. Eur J Haematol,1999,62:1-18
  • 4[4]Tang R, Chen HH, Wang YL, et al. Risk factors for surgical site infection after elective resection of the colon and rectum: a sin-gle-center prospective study of 2,809 consecutive patients. Ann Surg,2001, 234: 181-189
  • 5[5]Opelz G, Vanrenterghem Y, Kirste G, et al. Prospective evaluation of pretransplant blood transfusions in cadaver kidney recipients. Transplantation,1997,63:964-967
  • 6[6]Houbiers JG, van de Velde CJ, van de Watering LM,et al. Trans-fusion of red cells is associated with increased incidence of bacterial infection after colorectal surgery: A prospective study. Transfusion, 1997,37:126-134
  • 7[7]Kopko PM, Holland PV. Transfusion-related acute lung injury. Br J Haematol,1999,105:322-329
  • 8[8]Sowade O, Warnke H, Scigalla P, et al. Avoidance of allogeneic blood transfusions by treatment with epoetin beta (recombinant hu-man erythropoietin) in patients undergoing open heart surgery. Blood,1997,89:411-418
  • 9[9]Halpern NA, Alicea M, Seabrook B, et al. Isolyte S, a physiologic multielectrolyte solution, is preferable to normal saline to wash cell saver salvaged blood: Conclusions from a prospective, randomized study in a canine model. Crit Care Med,1997,25:2031-2038
  • 10[10]Ruttmann TG, James MFM, Aronson I. In vivo investigation into the effects of haemodilution with hydroxyethyl starch (200/0.5) and normal saline on coagulation. Br J Anaesth,1998,80:612-616

同被引文献23

  • 1甘建辉,陈杰,张景华,郭东勇,高鲁渤,邓迺封.用贺斯替代异体输血对肿瘤患者围术期免疫系统的影响[J].中国肿瘤临床,2005,32(15):861-863. 被引量:11
  • 2赵祎莉,江山平,王大强,黄广南.术中输血量与肝癌术后肺部并发症的关系[J].岭南现代临床外科,2007,7(1):41-42. 被引量:4
  • 3陈敬华,焦顺昌.280例非小细胞肺癌患者围手术期输血与否的预后关系[J].中国肿瘤临床,2007,34(11):632-635. 被引量:7
  • 4Bordin JO,Blajchman MA.Transfusion-associated immunosuppression[M] // Rossi EC,Simon TL,Moss GS,et al.Principles of transfusion medicine.2nd ed.Baltimore:Williams & Wilkins,1996:803-812.
  • 5Hanazaki K,Kajikawa S,Shimozawa N,et al.Perioperative bloodtransfusion and survival following curative hepatic resection for hepatocellular carcinoma[J].Heppatogastroenterology,2005,52(62):524-529.
  • 6Hebert PC,Wells G,Blajchman MA,et al.The Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group:A multicenter,randomized,controlled clinical trial of transfusion requirements in critical care[J].N Engl J Med,1999,340(6):409-417.
  • 7Edelman MJ,Potter P,Mahattey KG,et al.The potential for reintroduction of tumor cells during intraoperative blood salvage:reduction of risk with use of the RC-400 leukoyte depletion filter[J].vrology,1996,47(2):179.
  • 8BurrowsL,TartterP.Effect of blood transfusions on clolonic malignancy recurrent rate[J].Lancet,1982,2 (8299):662.
  • 9Woo Jin Hyung,MD,Sung Hoon Noh,MD.Adverse Effects of Perioperative Transfusion on Patients With Stage Ⅲ and Ⅳ Gastric Cancer[J].Ann of Surg Oncol,2002,9(1):5-12.
  • 10Bordin JO,Blajchman MA.Transfusion-associated immunosuppression.In Rossi EC,Simon TL,Moss GS,et al.Principles of Transfusion Medicine[M].2th edition.Baltimore:Williams & Wilkins,1996:803-812.

引证文献2

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部