姜黄三物汤治疗高胆红素血症120例临床观察

Clinical Observation on 120 Cases Suffered From Hyperbilirubmemia Treated by Jianghuangsanwu Decoction

目的 观察姜黄三物汤治疗高胆红素血症的临床疗效。方法 采用姜黄三物汤 (茵陈、姜黄、炒麦芽 )治疗新生儿黄疸 12 0例并与鲁米那组对比 ,观察其黄疸消退时间、肝功能、总胆红素等指标的变化。结果 姜黄三物汤具有明显的缩短退黄时间、降低胆红素及一定的降低谷丙转氨酶、谷草转氨酶、r-转肽酶等指标的作用 ,疗效均优于鲁米那组 (P <0 0 1或P <0 0 5 ) ,总有效率为10 0 % ,治愈率为 80 .33%。结论 姜黄三物汤具有显著的退黄作用及保肝作用 ,为治疗高胆红素血症简、验、廉的方药。

Objective The curative effect of Jianghuangsanwu Decoction used to treat hyperbilirubinemia was observed. Method 120 newborns with neonatal jaundic were treated with Jianghuangsanwu Decoction and contrasted with the group treated with luminal. The changes of some targets, such as jaundic decreasing time, the liver function and the total bilirubin, were observed as well. Result Jianghuangsanwu Decoction had remarkable effect on shortening jaundic decreasing time, reducing bilirubin, GPT, GOT and γ GT. The curative effect of this group was better than that of the group treated with luminal ( P <0 01, or P <0 05). The total effective rate was 100%, and the cure rate, 80 33%. Conclusion Jianghuangsanwu Decoction had remarkable effect on reducing jaundic and protecting the liver. Jianghuangsanwu Decoction was a simple, effective and reasonable prescription used to treat hyperbilirubinemia.