金属离子在细胞凋亡中的调控作用

Regulation and Control of Metal ion in Cell Apoptosis

综述了宏量金属(钙、钾、钠)和微量金属(锌、铜、铁、镉)等诱导细胞凋亡的概况。宏量金属是细胞内环境主要维持物,细胞凋亡时细胞内环境发生很大变化,宏量金属的量也会随之变化,成为标示细胞凋亡的一个特征;微量金属则是围绕细胞过氧化进行作用,主要讨论了微量金属影响细胞过氧化的机制;并对今后关于金属与细胞凋亡的研究提出了自己的一些建议。

This paper discusses the role of macro-like metal(calcium,kalium,natrium) and trace-like metal(zinc, copper, iron, cadmium) in death decision of cell. Macro-like metal maintains environment of cell. Intracellular environment will change when the program cell death is on the way .The quantity of macro-like metal will change too. It is the signal of apoptosis. Trace-like metals play a role in many aspects of cell . The oxidative effect on apoptosis is foccused on which is caused by trance-like metal,and the advice of future investigate is expressed.