摘要
以组分的连续性方程为基础 ,建立了药物从多孔骨架聚合物系统中释放的数学模型 .在模型中引入相对渗透速度来刻画药物释放过程中不同机理的影响 .对药物从多孔骨架聚合物系统中non Fickian扩散现象进行了研究 。
A mathematical model describing the drug release from porous polymer was established by using the species continuity equation.The relative permeating rate was introduced to describe the effects of the different physical processes.An asymptotic solution has been obtained by using the perturbation theory. The whole process of the drug release from porous polmer was analysized, especially the process controlled by drug dissolution.
出处
《山东大学学报(理学版)》
CAS
CSCD
北大核心
2003年第3期61-65,共5页
Journal of Shandong University(Natural Science)
基金
山东大学跨学科预研项目
关键词
连续性方程
多孔骨架聚合物
数学模型
Continuity equation
porous polymer
Mathematical model
perturbation theory