口腔鳞状细胞癌患者患源性诊断延误相关因素的回顾性研究

A retrospective study on factors related to delay in diagnosis of the patients with oral squamous cell carcinoma

目的 分析影响口腔鳞状细胞癌患源性诊断延误形成的相关因素。方法 对208例口腔鳞状细胞癌患者的性别、年龄、是否有就诊前治疗、主要就诊原因、发病部位、病变范围等因素进行多因素方差分析,探讨它们对口腔鳞状细胞癌患源性诊断延误的影响。结果 是否有就诊前治疗,就诊症状为肿物和患源性延误存在显著的正相关(P<0.05);肿瘤发病部位中,因为牙龈部位的鳞癌而来就诊的患者诊断延误时间相对要短;性别、年龄、病变范围与诊断延误没有联系。结论 患者有就诊前治疗及病变表现为肿物,能明显延长患源性延误;发病部位为牙龈的患者,诊断延误时间较短。

Objective Clinical factors related to delay in diagnosis of oral squamous cell carcinoma were investigated. Methods This was a clinical retrospective study. Two hundred and eight patients with oral squamous cell carcinoma were entered into the study. The multi - factor variance analysis was applied to look for the correlation between the time of delay in diagnosis and clinical factors of sex, age, whether having pre- diagnosis treatments, reasons for seeing doctors,lesion locations, and lesion size. Results Whether having pre - clinical treatments and the reason for seeing doctors(when tumor present as a mass) had positive correlations with the delay; while lesion location(when occured in gingiva) was negatively correlated, and the remaining factors had no significant influence on the delay. Conclusion Patients having prediagnosis treatments and with tumor presenting as a mass have a longer delay in diagnosis. When tumor occurs in gingiva the delay becomes shorter than the average.