摘要
目的 评估纳络酮在多巴胺难治性休克中的应用效果。方法 16例多巴胺治疗超过 2 4h的脓毒性休克病人 ,静脉大剂量注射纳络酮。结果 纳络酮平均应用 (6 .0± 3.5 )mg、(12 .6± 10 .1)h后 ,血压正常且撤除多巴胺 ,而此前多巴胺用量累计达 (777.5± 4 93.1)mg ,时间累计达 (36 .6± 10 .1)h。
Objective\ To determine the efficacy of naloxone infusion in septic shock patients refractory to dopamine.Methods\ 16 patients in septic shock which was refractory to dopamine over 24 h ,were received high-dose a naloxone intravenous infusion.Results\ After infusing naloxone (6.0±3.5) mg which lasted (12.6±10.1) h,the blood pressure resumed,and dopamine was withdrawn,while (777.5±493.1) mg dopamine had been supplied for (36.6±10.1) h.Conclusion\ These data indicate that high-dose naloxone may be a useful therapy in the management septic shock refractory.
出处
《医师进修杂志》
北大核心
2003年第7期18-19,共2页
Journal of Postgraduates of Medicine
