肠内营养对重症胰腺炎患者免疫功能的影响

The effects of early enteral nutrition on immune function of severe acute pancreatitis

目的 研究肠内营养对重症胰腺炎患者免疫功能的影响。方法 对我院自 2 0 0 1～2 0 0 2年 32例重症胰腺炎病人行肠内营养 (EN)的免疫球蛋白、细胞因子和红细胞免疫功能进行检测 ,并与 30例采用肠外营养 (TPN )的病人进行比较。结果 EN组应用 1周后IgA浓度明显提高 ,IL -6明显提高 ,IL -10显著下降 ,红细胞C3b受体花结率 (RRCR )明显提高。

Objective To study The effects of early enteral nutrition on immune function of severe acute pancreatitis.Methods Sixty-two patients with severe acute pancreatitis were divided into two groups,enteral nutrition group (EN group,32 cases)and total parenteral group (TPN group,32 cases).Immunoglubolin,cytokines and immune function of red celll were measured.Results Higher concentration of IgA was present,IL-6 increased and IL-10 decreased in EN group,enteral nutrition recovered the immune function of red cells.Conclusion The early enteral nutrition can improve the immune function of severe acute pancreatitis.