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噻唑烷二酮类药物治疗老年2型糖尿病21例 被引量:1

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摘要 目的:观察噻唑烷二酮类药物治疗老年2型糖尿病的效果。方法:对21例老年2型糖尿病(T2DM)患者在原降糖治疗基础上加用噻唑烷二酮类药物(罗格列酮或吡格列酮),治疗5月~1.5年,监测空腹血糖(FPG)、餐后2h血糖(2hPG)、糖基化血红蛋白(HbAlc)、肝肾功能、血脂、尿微量白蛋白和体重指数(BMI)。结果:FPG、2hPG和HbAlc较治疗前明显下降(P<0.01),原用降糖药减量或停用可维持疗效BMI增加(P<0.05),与胰岛素联用者可出现水肿和严重低血糖症。结论:噻唑烷二酮类药物单用或与其他降糖药联用,均可稳定持久降低血糖,老年T2DM患者有较好的耐受性,对与胰岛素联用者应密切监测血糖和心功能。
作者 邓晓初
出处 《中国药业》 CAS 2003年第7期65-66,共2页 China Pharmaceuticals
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