期刊文献+

乌司他丁治疗急性胰腺炎38例临床分析

下载PDF
导出
摘要 目的 :观察乌司他丁 (Ulinastatin ,UTI)治疗急性胰腺炎 (AP)的临床疗效。方法 :选取急性胰腺炎38例年龄 18~ 6 5岁 ,平均 5 1 6岁。分成两组 :观察组 2 0例 ;对照组 18例。两组均予传统治疗 ,观察组加用UTI10万U溶于 5 %葡萄糖注射液 5 0 0ml静脉滴注 (2~ 3h) ,2次 /天 ,3天后改为 10万U ,1次 /天 ,疗程 5~ 10天 ;对照组只用传统治疗 ,疗程 5~ 10天。分别观察两组治疗后症状、体征、血清及尿淀粉酶作比较 ,并作统计学处理。结果 :观察组治愈率为 85 0 % ,总有效率 95 0 %与对照组治愈率 6 6 7% ,总有效率 77 8%比较 ,差异有显著性 (P <0 0 5 )。结论 :乌司他丁对急性胰腺炎有明显抑制作用 ,疗效显著 ,使用安全 ,无明显毒副作用 。
出处 《广州医药》 2003年第4期32-34,共3页 Guangzhou Medical Journal
  • 相关文献

参考文献4

二级参考文献12

  • 1[1]Koizumi R,Kanai H,Maezawa A,et al.Therapeutic effects of ulinastatin on experimental crescentic glomerulonephritis in rats[J].Nephron,2000,84(4)∶347-353.
  • 2[2]Ohnishi H,Kosuzume H,Ashida Y,et al.Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis[J].Dig Dis Sci,1984,29(1)∶26-32.
  • 3[3]Okumura Y,Inoue H,Fujiyama Y,et al.Effects of serine protease inhibitors on accumulation of polymorphonuclear leukocytes in the lung induced by acute pancreatitis in rats[J].J Gastroenterol,1995,30(3)∶379-386.
  • 4[4]Matsukawa H,Hara A,Ito T,et al.Continuous arterial infusion of protease inhibitor with supplementary therapy for the patients with severe acute pancreatitis--clinical effect of arterial injection of ulinastatin[J].Nippon Shokakibyo Gakkai Zasshi,1998,95(11)∶1229-1234.
  • 5Dr. Moises Guelrud MD, FACG,Sonia Mendoza MD,Guillermo Rossiter MD,Maria I. Villegas MD.Sphincter of oddi manometry in healthy volunteers[J]. Digestive Diseases and Sciences . 1990 (1)
  • 6Grosman I,Simon D.Potiential gastrointestinal uses of somatostatin and its synthetic analogue octreotide. The American journal of Gastroenterology . 1990
  • 7Ahrendt SA,McGuire GE,Lillemoe KD,et al.Somatostatin inhibits sphincter of Oddi motility. Gastroenterology . 1990
  • 8Cai W,Gu J,Huang W,et al.Peptide immunoreactive nerves and cells of the guinea pig gallbladder and biliary pathways. Gut . 1983
  • 9Toouli J,Dodds WJ,Honda R,et al.Motor function of the opossium sphincter of Oddi. The Journal of Clinical Investigation . 1983
  • 10Toouli J.The functional integration of gallbladder and sphincter of Oddi motor activity in humans. Gastrointestinal Endoscopy . 1993

共引文献113

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部