配对t检验误区与率转化配对t检验方法介绍及各自应用范围

A Misapplication of the paired t - test and An Introdution of rate - transfer parired t-test method.

目的明确配对t检验误区与率转化配对t检验方法及各自应用范围,以使医学实践与实验研究的结果判断更为科学、准确。方法对医学实践与实验研究中遇到的具体事件,用配对t检验与率转化配对t检验进行比较。结果与治疗、稀释、保存有关的事件常规配对t检验结果无显著性差异,而采用率转化配对t检验结果有显著性或非常显著性差异;成定值改变的事件用率转化配对t检验无显著性差异,而用常规配对t检验结果有显著性差异。结论与治疗、稀释、保存有关的事件且原个体差别悬殊,应采用率转化配对t检验;而成定值的事件应采用原配对t检验。

Objective To identify the misapplication of the paired t - test and define the condifion of using rate - transfer t - test method, in order to achieve more scientific and exact results of conducting practice of medical and laboratory. Methods To contrast the methods of paired t - test misapplied and rate - transfer paired t - test in dealing with the data of medical and laboratory. Results The conventional paired t - test for the events relating to treatment, dilution and preservation showed no significant difference, however the rate - transfer paired t - test for the same events showed significant or very significant differenee, on the contrary, the rate - transfer paired t - test for the events with the change of fixed value showed no significant difference, but the conventional paired t - test for the same events showed significant difference. Conclusions The rate - transfer paired f - test for the events, with a great disparity amongg the original Individuals, relating to treatment, dilution and preservatiao should be introduced but the conventional paired t - test for the events with the change of fixed value should be adopfed .