介入治疗在肝癌术后复发中的作用及效果研究

Clinical Observation of the Effect and Effect of Interventional Therapy in the Recurrence of Hepatocellular Carcinoma

目的分析介入治疗在肝癌术后复发中的价值。方法选取2013年12月—2016年12月于广州军区广州总医院接受治疗的肝癌术后复发患者78例,将其随机分为对照组和观察组,每组各39例。对照组患者于肝癌切除术后接受化疗治疗,观察组接受介入治疗。评估两组的疗效,记录不良反应,并计算1年生存率。结果观察组总有效率高于对照组(χ~2=4.044,P=0.044)。观察组术后1年生存率为56.4%(22/39),高于对照组的33.3%(13/39)(χ~2=4.048,P=0.040)。两组不良反应发生率比较,差异无统计学意义(χ~2=0.743,P=0.389)。结论介入治疗可有效预防肝癌术后复发,提高患者的生活质量,提高生存率,建议推广。

Objective To analyze the value of interventional therapy in recurrence of hepatocellular carcinoma after operation.Methods Seventy-eight patients with recurrence of liver cancer who were treated at Guangzhou General Hospital of Guangzhou Military Region from December 2013 to December 2016 were randomly divided into control group and observation group,with 39 cases in each group.The control group received chemotherapy after liver cancer resection and the observation group received interventional therapy.The efficacy of the two groups was assessed,adverse events were recorded,and 1-year survival rates were calculated.Results The total effective rate of the observation group was higher than that of the control group(χ~2=4.044,P=0.044).The 1-year survival rate was 56.4%(22/39)in the observation group,which was higher than 33.3%(13/39)in the control group(χ~2=4.048,P=0.040).There was no significant difference in the incidence of adverse reactions between the two groups(χ~2=0.743,P=0.389).Conclusion Interventional therapy can effectively prevent recurrence of hepatocellular carcinoma after operation,improve the quality of life of patients,improve survival rate,it is recommended to promote.