摘要
痛风发作期间,79%的患者会因疼痛及住院治疗无法正常工作,严重影响患者的工作和生活质量,其长期治疗目标是降低血尿酸水平,减少急性发作,改善患者预后。痛风患者血尿酸达标率低,与其降尿酸治疗依从性不佳有关。本文将痛风患者治疗依从性的影响因素,分为社会人口学因素、患者因素、医疗团队因素、疾病相关因素及治疗相关因素5个方面进行了总结,并指出提高其服药依从性的可能的干预措施。
Gout has a direct impact on the quality of work and daily lives.79% of the patients can not work due to pain and hospitalization during gout flares.The goal of long-term therapy is to lower the serum urate level to reduce recurrent acute gout flares and improve prognosis of patients.Researches have demonstrated that low serum urate control rate is associated with poor adherence to urate-lowering therapy.This article reviews 5 factors that influence adherence to urate-lowering therapy in patients with gout,including sociodemographic,patient-related,healthcare team-related,condition-related and therapy-related,and discusses potential interventions to improve the adherence to urate-lowering therapy.
作者
李博涵
方卫纲
沙悦
LI Bohan;FANG Weigang;SHA Yue(Department of General Practice,Chinese Academy of Medical Sciences&Peking Union Medical College,Division of General Internal Medicine,Peking Union Medical College Hospital,Beijing 100730,China;Department of Internal Medicine,Jiahui International Hospital,Shanghai 200030,China;Division of General Internal Medicine,Peking Union Medical College Hospital,Beijing 100730,China)
出处
《中国全科医学》
CAS
北大核心
2019年第7期865-869,共5页
Chinese General Practice
基金
公益性行业科研专项项目(201502024)
