尿微量白蛋白检测老年高血压早期肾损害的临床意义分析

Clinical significance of urinary Microalbumin in detecting early Renal damage in elderly patients with Hypertension

目的研究与分析尿微量白蛋白检测老年高血压早期肾损害的临床意义。方法选取浙江省杭州市余杭区第五人民医院收治的老年高血压早期肾损害患者50例为观察组,同期选择健康体检者50例为对照组。回顾性分析两组相关基础资料,其均接受尿微量白蛋白检测,比较两组尿微量白蛋白检测水平以及阳性率,分析尿微量白蛋白诊断患者早期肾损害的临床意义。结果经检测,观察组尿微量白蛋白水平较对照组显著较高(P<0.05);而观察组尿微量白蛋白阳性率74.0%较对照组8.0%显著较高(P<0.05)。而老年高血压患者不同分级间(Ⅰ级、Ⅱ级、Ⅲ级)尿微量白蛋白水平逐渐升高,且各级之间对比差异有统计学意义(P<0.05)。结论在临床诊断老年高血压早期肾损害患者的过程中,应用尿微量白蛋白检测的效果显著,即该指标可准确评估患者的肾损伤情况,因此值得临床应用推广。

Objective To study and analyze the clinical significance of urinary microalbuminuria in the detection of early renal damage in elderly patients with hypertension.Methods 50 elderly hypertensive patients with early renal damage were selected as the observation group and 50 healthy subjects as the control group at the same time.The related basic data of the two groups were analyzed retrospectively.The urine microalbumin levels and positive rates were compared between the two groups.The clinical significance of urinary microalbumin in the diagnosis of early renal damage was analyzed.Results The level of urinary microalbuminuria in the observation group was significantly higher than that in the control group(P<0.05),while the urine albumin positive in the observation group was significantly higher than that in the control group.The sexual rate of 74.0%was significantly higher than 8.0%of the control group(P<0.05).The level of urinary microalbuminuria in elderly patients with hypertension increased gradually among different grades(gradeⅠ,gradeⅡ,gradeⅢ),and there was significant difference between different grades(P<0.05).Conclusion In the process of clinical diagnosis of early renal damage in elderly patients with hypertension,urinary microalbuminuria has a significant effect,that is,the index can accurately evaluate the renal injury of the patients,so it is worthy of clinical application and popularization.