促肝细胞生成素联合阿拓莫兰治疗失代偿期肝硬化的临床研究(附45例分析)

The effect of prohepatocyte growth factor(PHGF)and atuomulan on hepatic cirrhosis with disfunction

目的 观察促肝细胞生成素与阿拓莫兰联合治疗失代偿期肝硬化的临床疗效。方法 4 5例失代偿期肝硬化患者随机分为治疗组 2 0例及对照组 2 5例 ,治疗组应用促肝细胞生成素 80 mg及阿拓莫兰 12 0 0 mg静脉滴注 ,对照组采用阿拓莫兰 12 0 0 m g静脉滴注 ,两组同时给予支持等综合治疗 ,疗程共 4周 ,观察治疗后患者症状、体征及肝功能等变化。结果 疗程结束后治疗组患者症状、体征及肝功能状况的改善均明显优于对照组。

Objective To observe the effect of prohepatocyte growth factor(PHGF)and atuomulan on hepatic cirrhosis with disfunction.Methods 45 patients with hepatic cirrhosis were randomly divided into treatment group(n=20)and control group(n=25),PHGF 80mg and atuomulan 1200mg were used to intervenous drip in treatment group and atuomulan 1200mg was used to intervenous drip in control group for 4 weeks,while two groups were given multiple treatment,observing the changes of symptoms,signs and hepatic function after treatment.Results The improvement of symptoms,signs and hepatic function in treatment group was superior to control group.Conclusion The union application of PHGF and atuomulan has a good effect on hepatic cirrhosis with disfunction.