探析血液恶性肿瘤患者化疗后口腔感染的相关危险因素

Risk factors of oral infection in patients with hematological malignancies after chemotherapy

目的对血液恶性肿瘤患者化疗后口腔感染的相关危险因素进行分析和探究。方法选取我院2012-04-2015-04收治的接受化疗的血液恶性肿瘤患者74例为研究对象,利用多种方法对化疗结束后口腔感染发生的危险因素进行相关分析,同时提出相关预防措施。结果颊部和牙龈是口腔感染发生率较高的部位,口腔感染的发生率与患者大部分临床资料呈正相关关系,口腔感染发生的高风险因素主要有年龄、血清白蛋白水平在40g/L以下、粒细胞绝对值在0.5×109 L-1以下、口腔环境差、口腔自洁习惯差、多次化疗周期、化疗未缓解几种。结论血液恶性肿瘤患者进行化疗后导致口腔感染发生的因素有很多,必须采取针对性预防措施干预导致口腔感染发生的因素,减少口腔感染的发生,提升患者的生命质量。

OBJECTIVE To analyze and explore the risk factors of oral infection in patients with malignant tumor after chemotherapy.METHODS Selected in our hospital from April April 2012 to 2015accept chemotherapy in patients with hematological malignancies in 74 cases as the research object,using a variety of methods of chemotherapy.RESULTS Cheek and gum is oral infection rates were higher in the site,oral infection occurrence rate and most of the patients clinical data were positively correlated,oral infection of high risk factors mainly include age,serum albumin level below the 40g/L,granulocyte absolute value0.5×109/L below.CONCLUSION Chemotherapy in patients with hematologic malignancies in oral infection of many factors,we must take targeted prevention and intervention factors leading to oral infection.