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细胞周期蛋白E1与卵巢上皮性肿瘤关系探讨

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摘要 目的探讨细胞周期蛋白E1与卵巢上皮性肿瘤关系。方法本研究的对象均为2013-12-2015-12我附属医院就诊的卵巢疾病患者,共80例,其中良性卵巢上皮性肿瘤患者40例,卵巢上皮癌患者40例,同时选择同时期在我附属医院体检的正常卵巢者40例,比较3组卵巢上皮组织中的细胞周期蛋白E1。结果卵巢上皮癌患者、良性卵巢上皮肿瘤患者和卵巢正常者的细胞周期蛋白E1表达水平分别为(185.29±10.14)、(155.37±9.35)和(126.16±8.23),依次降低,组间比较差异有统计学意义,P<0.05。结论卵巢上皮性肿瘤患者的细胞周期蛋白E1明显高于正常者,并且癌症越严重,细胞周期蛋白E1水平越高,临床上可以将细胞周期蛋白E1作为筛查诊断卵巢上皮性肿瘤的指标。
出处 《中华肿瘤防治杂志》 CAS 北大核心 2016年第S2期260-261,共2页 Chinese Journal of Cancer Prevention and Treatment
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