不同手术方式治疗子宫肌瘤对妇科内分泌状态的影响

The effect of different surgical methods on gynecological endocrine state of uterine leiomyoma

目的对比单纯腹腔镜下子宫血管阻断术与联合子宫肌瘤剜除术治疗子宫肌瘤对患者妇科内分泌状态的影响。方法选取我院妇科收治的80例子宫肌瘤患者作为研究对象。随机将其分为两组各40例,A组接受单纯腹腔镜下子宫血管阻断术治疗,B组则接受腹腔镜下子宫血管阻断术联合子宫肌瘤剜除术治疗,比较两组治疗效果及内分泌状态变化情况。结果两组术中出血量、术后排气时间比较无显著差异(P>0.05),但B组住院时间明显低于A组,而手术用时明显高于A组,P<0.05;术前两组E2、FSH、LH、P水平比较无显著差异(P>0.05),术后3个月B组E2明显低于对照组,FSH水平明显高于对照组,P<0.05;而两组LH、P水平比较无显著差异(P>0.05);术后6个月两组E2、FSH、LH、P指标比较均无显著差异(P>0.05)。结论腹腔镜下子宫血管阻断术联合子宫肌瘤剜除术可有效提升子宫肌瘤的临床治疗效果,并且对患者内分泌激素影响较小,具有疗效可靠、安全性高的优点。

OBJECTIVE Compare the effects of laparoscopic uterine vascular occlusion and combined hysteromyoma enucleation on gynecological endocrine status of patients with uterine leiomyoma.METHODS From gynecology was selected in our hospital.80 patients with uterine leiomyoma were randomLy divided into two groups:group A(40 cases)and group B(40 cases)received laparoscopic uterine vascular occlusion.,RESULTS Blood loss during operation and exhaust time after operation were compared between the two groups.There was no significant difference(P>0.05),but the level of E2 in group B was significantly lower than that in the control group 3 months after operation(P<0.05),but there was no significant difference between the two groups in the level of LHHU P(P>0.05).There was no significant difference between the two groups in E2 FSHS LHP index(P>0.05).CONCLUSIONS Laparoscopic uterine vascular occlusion combined with uterine myomectomy is of no significance(P>0.05).Removal of uterine leiomyoma can effectively improve the clinical treatment effect,and has less effect on endocrine hormone,has the advantages of reliable curative effect and high safety.