机体毒鼠强负荷与临床表现关系的研究

Observation of the relationship between tetramine concentration in vivo and clinical manifestations

目的 探讨血、尿毒鼠强含量在毒鼠强中毒诊断中的价值。方法 统计分析毒鼠强中毒患者抽搐类型、意识障碍程度、取样时间与血、尿毒鼠强量的关系。结果 血、尿毒鼠强含量随抽搐加重、意识障碍程度加深而增加。全身抽搐患者血、尿毒鼠强量非常显著高于局部抽搐、无抽搐者。重度意识障碍患者非常显著高于轻度意识障碍、无意识障碍者。取样当时、取样当天的血、尿毒鼠强量与抽搐类型、意识障碍程度的关系相似。结论 血、尿毒鼠强量是毒鼠强中毒诊断的特异指标 ,根据血、尿毒鼠强量可将毒鼠强中毒分为轻、重二型。

Objective To investigate the clinical value of tetramine concentration in plasma and urine in diagnosis of tetramine poisoning. Method To analyse the relationship of epilepsia classification, disturbance of consciousness, sampling time and tetramine concentration in plasma and urine. Result Tetramine concentration in vivo increased when epilepsia and disturbance of consciousness got badly. Tetramine concentration was significantly higher in severe disturbance of consciousness than in light one. Conclusion Tetramine concentration in vivo was specific index, according to it we divided tetramine poisoning into light and severe.