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静脉滴注尼卡地平治疗老年人高血压危象的临床观察 被引量:5

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摘要 目的 观察静脉滴注尼卡地平对老年人高血压危象的疗效及安全性。方法 选择老年人 (≥ 6 0岁 )高血压危象患者 92例 ,治疗前平均收缩压 (SBP) (2 36± 16 )mmHg和 (或 )舒张压 (DBP) (12 5± 11)mmHg ,以恒速输液泵持续静脉滴注尼卡地平 (佩尔地平 ) ,剂量为 0 5~ 6 μg·kg-1·min-1,根据血压每 5min调整剂量 1次 ,每次增加 5 μg/min ,直至达到目标血压 15 0~ 16 0 /10 0~ 110mmHg,然后维持此血压水平 1~ 3d。结果 用药后 5min、10min、30min、1h、2h的平均血压降至 2 31/12 5、2 2 6 /12 3、2 17/12 1,2 0 7/118、2 0 3/10 7mmHg ,2 4h后达最大效应 ,血压平均为 (16 8± 11) /(10 0± 9)mmHg ,并稳定至用药结束。未发现严重不良反应。结论 静脉滴注尼卡地平治疗老年人高血压危象起效快、降压作用平稳、安全性高。
出处 《中国急救医学》 CAS CSCD 北大核心 2003年第8期576-577,共2页 Chinese Journal of Critical Care Medicine
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共引文献10

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