摘要
在单因素考察的基础上采用均匀设计法制得莪术油微囊 (CAO- MC) ,对其制备工艺、理化性质及含量进行了研究 ,所得微囊形态圆整 ,平均粒径为 77.3μm,粒径符合正态分布。研究结果显示所制得的 CAO- MC中莪术醇含量 1.35 1% ,有可能试用于肝动脉栓塞。
A uniform design was used to optimize the preparation technology of curcuma aromatic oils microcapsules(CAO-MC) on the basis of single factor pretests. The formulation, physicochemical characteristics and drug content of the CAO-MC were studied. The CAO-MC were spherical with a mean diameter of 77.30 μm, and the size distribution conformed with normal distribution. Curcumenol content was 1.351%. The results showed that the prepared CAO-MC might be used for embolization.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2003年第8期391-392,共2页
Chinese Journal of Pharmaceuticals
关键词
莪术油
微囊
栓塞剂
制备气相色谱法
curcuma aromatic oils
microcapsules
embolization
preparation
GC
