冠状动脉侧支循环与年龄、性别因素的关系

Relation between sex,age and coronary collateral circulation

目的 探讨冠状动脉侧支循环的形成与年龄、性别因素的关系。方法 将 1997年 1月至 2 0 0 2年 3月经冠状动脉造影证实至少一只冠状动脉血管直径狭窄≥ 75 %的 2 6 5例冠心病患者为入选对象 (排除瓣膜病、先天性心病、心肌病和肺心病 )。将显示有侧支的患者以 5 5和 6 5岁为界 ,分成年轻组、中年组及老年组 ,初步分析年龄及性别因素与侧支循环开放率之间的关系。结果 冠心病患者冠状动脉侧支开放率与年龄有关 ,5 5～ 6 5岁年龄组侧支开放率最高 ,女性因生理原因冠状动脉病变发生较晚 ,故侧支开放明显滞后 ,在 6 5岁以后冠状动脉侧支开放率仍低于男性 ,差别有统计学意义。结论 冠心病患者冠状动脉侧支开放率与年龄有关 。

Objective To study the relationship between sex,age and coronary collateral circulation.Methods A cohort of 265 patients with ≥75% luminal diameter stenosis involving at least one major coronary artery diagnosis drawn from 694 patients by selective coronary angiography was retrospectively analysed on their angiographic features and interaction between coronary artery stenosis,age,sex with coronary microcirculation from January 1997 to March 2002.Results The prevalence of collateral circulation in middle aged group being significantly higher than younger and older groups.A significantly greater collateral proportion appeared in women than men in old group (age >65 years old).Men′s coronary collateral circulation is more than women even in olderage group (P< 0.05 ).Conclusions Coronary couateral circulation is relationship to age and sex.Men′s coronary collateral circulation is more than women even is olderage group(P< 0.05 ).