离子液体促进的正丁醛缩合制备2-乙基-2-己烯醛反应研究

Studies of the preparation of 2-ethyl-2-hexenal from the condensation of n-butyraldehyde promoted by ionic liquids

研究了氢氧化钠催化正丁醛缩合生成2-乙基-2-己烯醛的反应条件,产物收率为76.5%。将两种离子液体应用于该反应,考察了离子液体用量对收率的影响。结果表明,在正丁醛缩合反应中加入离子液体溴代1-丁基-3-甲基咪唑或1-丁基-3-甲基咪唑磷酸二丁酯,产物收率明显提高,分别可以达到93.2%和89.4%。产物结构由核磁共振氢谱进行表征。

The reaction conditions of condensation were studied which transferred the n-butyraldehyde to 2-ethyl-2-hexenal catalyzed by sodium hydroxide with 76.5%yield. Two kinds of ionic liquids were used in this reaction. The influence of the amount of ionic liquids on the yields were studied. The results showed that the reactions were improved significantly by ionic liquids 1-butyl-3-methylimidazolium bromide and 1-butyl-3-methylimidazolium dibutylphosphate,and the yields were improved to 93.2%or 89.4%respectively. The structure of products were characterized by 1 H NMR.